Anti-HIV-1 activity of Sargassum swartzii a marine brown alga

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Anti-HIV-1 activity of Sargassum swartzii a marine brown alga

Methods The HIV inhibitory activity of aqueous and methanolic extracts of S. swartzii was determined on laboratory adapted strains of HIV-1 clades C and A by indirectly measuring reduction in HIV-1 gag p24 antigen levels and inhibition of HIV-1 RT activity in supernatants of virus infected donor peripheral blood mononuclear cell (PBMC) cultures grown in varying concentrations of the extracts. P...

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Phytochemical Characterization of Marine Macro Alga Sargassum polycystem, Molecular Docking, and In Vitro Anti-bacterial Activity against Psuedomonas aeruginosa

Marine macro algae are useful to mankind as food, biofertilizer, and source of bioactive compounds such as agar-agar, alginates, and carrageenan. The aim of this study was to explore the phytochemicals, and the antibacterial activity of the marine alga Sargassum polycystem. The marine alga was subjected to ethanolic and methanolic extractions. The preliminary screening for phytochemicals showed...

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Larvicidal activity of marine algae, Sargassum swartzii and Chondria dasyphylla, against malaria vector Anopheles stephensi.

OBJECTIVES The objective of this study was to evaluate larvicidal activity of native marine algae against main malaria vector Anopheles stephensi. STUDY DESIGN The total 70% methanol (MeOH) extract and partition fractions of chloroform (CHCl3), ethylacetate (EtOAc), and MeOH from two algae, Sargassum swartzii and Chondria dasyphylla were investigated for larvicidal activities against late III...

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Fibrinolytic Compounds Isolated from a Brown Alga, Sargassum fulvellum

Two of bioactive natural products were founded in a brown alga, Sargassum fulvellum. After isolation and purification, the molecular structures of these two products were investigated by NMR spectroscopy and GC-mass spectroscopy. The two compounds were identified to be 1-O-palmitoyl-2-O-oleoyl-3-O-(alpha-D-glucopyranosyl)-glycerol (POGG) and 1-O-myristoyl-2-O-oleoyl-3-O-(alpha-D-glucopyranosyl)...

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α-Glucosidase and Protein Tyrosine Phosphatase 1B Inhibitory Activity of Plastoquinones from Marine Brown Alga Sargassum serratifolium

Sargassum serratifolium C. Agardh (Phaeophyceae, Fucales) is a marine brown alga that belongs to the family Sargassaceae. It is widely distributed throughout coastal areas of Korea and Japan. S. serratifolium has been found to contain high concentrations of plastoquinones, which have strong anti-cancer, anti-inflammatory, antioxidant, and neuroprotective activity. This study aims to investigate...

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ژورنال

عنوان ژورنال: BMC Infectious Diseases

سال: 2014

ISSN: 1471-2334

DOI: 10.1186/1471-2334-14-s3-e43